In the beginning of your story, the hero and villain meet each other and embark on a journey. This journey can be a plane trip, a business merger, an experimental medical treatment, a wedding, etc.
In the middle of your story, the hero and villain begin to compete with each other instead of cooperating with each other.
The end will be the confrontation and resolution in which only one of these characters survives or triumphs. During the three phases of your story, each character experiences conflict and the trauma that comes with it.